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DEBATE: Lethal genes on Equiverse

ForumsEquiverse Chat → DEBATE: Lethal genes on Equiverse

DEBATE: Lethal genes on Equiverse

#103571 Posted on 2017-05-04 02:01:24

I support that idea.
It's not complicated to avoid loosing foals when breeding, just don't breed two Overo or White horses together.

To be honest, I was surprised that lethal genes weren't mentioned in game when I joined it o.O .
EDIT:
When breeding W+ x W+ (and also Oo x Oo) you have 25% chance for lethal (WW/OO), 50% for White/Overo (W+/Oo) and 25% for recessive (++/oo).
When breeding W+ x ++ (or Oo x oo) you get 50% to get W+/Oo horse, 50% for recessive (++/oo) and you won't for sure get lethal here.

Last edited on 2017-05-04 at 02:06:48 by Radosny Rabarbar


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#103591 Posted on 2017-05-04 05:58:14

Lol still going to cull if that happens XD besides those are the only ones I have currently,if I get more stores and the future foals of all of them  (or grand foals) down the line could end up having either of those things because I don't know how to breed away from them as genetics confuse me and I'm also not the best at remembering these types of things. 

Besides when people tell me don't or can't, it's in my nature  (as long as it's not harmful to me anyways) to do just that. Just ask the guy who said I couldn't make it up one mountain where I went and did a higher one to show him or the guy who thought I shouldn't go to the bottom of the grand canyon and I did it. Watching him eat his words was the best thing ever XD Now I have strayed a bit from what this topic was about so, still against it because brain can't handle all that, let alone regular genetics, and because for me I like not having to think about things :) and yep, still going to cull the breeds, which especially for the Shetlands will be great for some breeders I'm sure:)

Last edited on 2017-05-04 at 05:59:25 by Wonder Wiki


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#103606 Posted on 2017-05-04 08:13:31

It is if I was breeding strictly for color. 90% of my horses are bred with conformation in mind, so it may happen that I pair 2 white horses together for conformation. But still I used color randomizers on 3 herds of Lippys to get rid of grey, so yeah if it's added more money for the site lol 


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#103607 Posted on 2017-05-04 08:20:15

I'll probably end up culling all of my breeds that have the possibility of lethal.

I mean.. you wouldn't exactly need to stop breeding those breeds.  Just don't breed any horses that are Oo to another Oo because that's the only time it could happen.  And even then it's a 25% chance.

I more meant that it appears through people's research (from what's been said on an Equine genetics page) that only about 25% of an Overo x Overo results in a LWO foal, not that in 25% of cases the foal survives.

That's pretty much how it would work, the same as all other genes currently work in the game.  If you currently breed Ee and Ee, you have the 25% chance to get EE, for example.  When you mentioned 25% of lethal I was like.. huh, so it's not a sure thing if you breed OO? :P that's where my confusion came in.

Just curious, would you handle these two lethal genes the same way, with the mare having a normal pregnancy then giving birth to a foal that dies, or would you do that just for OO foals, then have mares carrying WW foals just stop being pregnant after a day, and maybe be able to be bred immediately?

From a coding point of view they would be handled the same way, but would maybe have different messages.  My main concern with the WW method is that people would go back to not caring about breeding W+ and W+ because if they get a lethal foal then meh, the breeding would just reset anyway.  I could always implement the normal post-birth cooldown (2 days) in which case, I suppose?


If this was to be implemented, if you went to breed two horses that had their genes revealed and were both Oo or both W+, I would show a message on the breeding page right above the button.  Something along the lines of:

Wait!  These two horses both have a dominant Overo allele.  It's possible for these two horses to breed a Lethal White foal - are you sure you want to continue?

Would that help at all if this was to be added?


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#103611 Posted on 2017-05-04 08:46:58

I wouldnt mind that if it had the warning for sure : D


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#103612 Posted on 2017-05-04 08:52:12

I think that would defiently be better to have a warning.


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#103620 Posted on 2017-05-04 09:58:24

I like having the warning, especially for those who may be unfamiliar with the genes.


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#103623 Posted on 2017-05-04 10:09:01

Definitely would like the warning to be displayed for those players who struggle with understanding genetics. 


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#103673 Posted on 2017-05-04 15:44:15

I would support it more with the warning :D


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#103684 Posted on 2017-05-04 16:26:05

I voted no. I prefer fun games over 'realistic' ones.

Alternately, if one fatal condition is added, then all potentially fatal conditions should be added. 


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#103686 Posted on 2017-05-04 16:31:04

I'm perfectly fine with the notion.

However, I will state that not all white genes are lethal. There's 20+ different genes all lumped under the category of "white". Aptly named W1-W20. Several of these can exist in homozygous forms, notably W20.

See: http://www.vgl.ucdavis.edu/services/horse/dominantwhite.php


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#103694 Posted on 2017-05-04 17:51:44

I am all for this.

Of course I'm a realism and genetics junkie.

And as Kuk said, not all W mutations are lethal. I believe the only one that is CONFIRMED homozygous lethal is the one found in Camarillo White Horses, which aren't even in the game anyway.


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#103734 Posted on 2017-05-04 22:00:31

@Abbey
With the warning, how would that work if the parents aren't gene tested? For example one parent is white with overo underneath (so there's no way to tell it's got overo) and the other is overo, which is known either with or without a test. Both parents have overo, but there's no way to tell for one of them until the warning comes up.
In general I support the idea of a warning though, just wondering how things will work.

@Kuk and vos
Although there are lots of different dominant white genes, only a few of these produce solid white horses, and most of those have either been proven to be homozygous lethal, or at least have strong evidence indicating they are, so it still makes sense to make the game's white gene homozygous lethal. Most of the dominant white genes produce white spotting, not solid white, so if those ones aren't lethal it's irrelevant.


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#103797 Posted on 2017-05-05 11:39:07

Most have them have /not/ been proved to be homozygous lethal. The vast bulk of them are only hypothesized to be homozygous lethal. Currently, there isn't enough DNA'd horses to be able to make an accurate guess.

If you recall, people thought that roan was homozygous lethal for quite some time.


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#103811 Posted on 2017-05-05 13:36:20

Most aren't homozygous lethal, actually.

And many of them simply aren't seen homozygous because they are specific to families, stemming from a singular horse. In order for a horse to be homozgyous for the vast majority of any of the white mutations would be if they were either closely linebred or directly inbred, which most people don't actually do. The breed with the most W mutations discovered right now is the Thoroughbred, and racing TB breeders generally do not want color so they tend not to really breed those that have a lot of white.

^ Yup. People thought roan was homozygous lethal for YEARS. Since roan is on KIT and KIT is extremely unstable, it's highly likely that there are multiple mutations of roan as well. There is a probable homozygous lethal version of roan in one of the European draft breeds, I believe.

Side note, it's actually been noticed by geneticists that many tested nearly or all-white horses with their family's mutation also have W20, which is a white booster. In horses from those families that have their family-specific mutation, but not W20, have spotting pattern but are not all white. And a couple years ago, equine geneticists renamed "dominant white" to "white spotting" BECAUSE the mutations don't result in a dominantly-white pattern without additional mutations boosting them.

Last edited on 2017-05-05 at 13:40:43 by vōs♚


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